Shout Triple-Acting Stain Remover Refill is packed with stain-fighting ingredients and enzymes to penetrate, break up and remove tough stains. It's 50 times more powerful than in-wash powder. This value-size Shout stain remover refill can be used with any Shout trigger bottle. The formula is suitable for any water temperature. It comes in a 60 fl oz bottle with a convenient handle for easy pouring.