What's in Estroven? Estroven's line of multi-symptom menopause relief products have been developed with many ingredients that either reside in nature or are naturally sourced, that have a relatively long safety profile history and demonstrated efficacy supporting their use to relieve peri/menopausal symptoms. Many of the ingredients used have been around for centuries and have a long history of providing menopausal symptom relief. Others have only recently been discovered as scientists begin to better understand the bioavailable nutrients that are most beneficial in reducing peri/menopausal symptoms. Safe & Natural Ingredients. The two major dietary ingredients used by the Estroven brand are clinically proven soy iso flavones and/or Black Cohosh, since these address the.